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|Product Name||CEBP-gamma (DNA binding domain, residues 39-147, Human)|
|Background||CCAAT/enhancer binding protein(C/EBP) gamma is a family of transcription factors all contain a highly conserved, basic-leucine zipper domain at the C-terminus that is involved in dimerization and DNA binding. C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP family consist of several related proteins, C/EBP alpha, beta gamma, delta, that form homodimers and/or form heterodimers with each other. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein; a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. C/EBP gamma may cooperate with Fos to bind PRE- enhancer elements. The DNA binding domain of CEBP-gamma (amino acid residues, 39-147) was produced in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||CEBPG, CEBP-gamma, His-tag (DNA binding domain, residues), C/EBP gamma, CCAAT/enhancer-binding protein gamma, CCAAT/enhancer binding protein g C/EBP gamma, CCAAT/enhancer binding protein (C/EBP) gamma, CCAAT/enhancer binding protein gamma, GPE1BP, IG/EBP 1, IG/EBP1,|
|AA Sequence||MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMPGG GGKAVAPSKQ SKKSSPMDRN SDEYRQRRER NNMAVKKSRL KSKQKAQDTL QRVNQLKEEN ERLEAKIKLL TKELSVLKDL FLEHAHNLAD NVQSISTENT TADGDN|
|Molecular Weight||14 kDa (129 aa), confirmed by MALDI-TOF.|
|Form||Liquid, in Phosphate-Buffered Saline (pH 7.4) , 40%glycerol, 2mM DTT, 0.1mM PMSF, 1mM EDTA|
|Concentration||0.5 mg/ml (determined by Bradford assay)|
|Purity||> 95% by SDS-PAGE|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Hattori,T., et al (2003) Oncogene 22(9). ,1273-1280
Davydov,I., et al(1995) Gene. 161(2) ; 271-275
Williams, S.C.,et al (1991) Genes Dev. 5(9) ; 1553-1567
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