CFD, 26-253aa, Human

Catalog
01-P1877
$0.00
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Proteins, Recombinant
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More Information
Product Name CFD, 26-253aa, Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MILGGREAEA HARPYMASVQ LNGAHLCGGV LVAEQWVLSA AHCLEDAADG KVQVLLGAHS LSQPEPSKRL YDVLRAVPHP DSQPDTIDHD LLLLQLSEKA TLGPAVRPLP WQRVDRDVAP GTLCDVAGWG IVNHAGRRPD SLQHVLLPVL DRATCNRRTH HDGAITERLM CAESNRRDSC KGDSGGPLVC GGVLEGVVTS GSRVCGNRKK PGIYTRVASY AAWIDSVLA
Applications SDS-PAGE
Background CFD, also known as adipsin, is involved in the alternative complement pathway of the complement system where it cleaves factor B. This protein is a member of the trypsin family of peptidases. It is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. It is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, it has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. Recombinant human CFD protein, fused to His-tag at N-terminus, was expressed in E.coli.
Concentration 0.5 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Species Human
Host E.coli
Intended Use For Research Use Only
Molecular Weight 15.4kDa (136aa), confirmed by MALDI-TOF
NCBI Accession # NP_001919
Purity > 85% by SDS-PAGE
References Narayana SV. et al. (1994) J Mol Biol. 235:695-708.
Ronti T. et al. (2006) Clin Endocrinol (Oxf). 64:355-365.
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms Complement factor D, DF, AND, PFD, ADIPSIN
Tag His-tag

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