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|Product Name||CHGB, 21-677aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MPVDNRNHNE GMVTRCIIEV LSNALSKSSA PPITPECRQV LKTSRKDVKD KETTENENTK FEVRLLRDPA DASEAHESSS RGEAGAPGEE DIQGPTKADT EKWAEGGGHS RERADEPQWS LYPSDSQVSE EVKTRHSEKS QREDEEEEEG ENYQKGERGE DSSEEKHLEE PGETQNAFLN ERKQASAIKK EELVARSETH AAGHSQEKTH SREKSSQESG EEAGSQENHP QESKGQPRSQ EESEEGEEDA TSEVDKRRTR PRHHHGRSRP DRSSQGGSLP SEEKGHPQEE SEESNVSMAS LGEKRDHHST HYRASEEEPE YGEEIKGYPG VQAPEDLEWE RYRGRGSEEY RAPRPQSEES WDEEDKRNYP SLELDKMAHG YGEESEEERG LEPGKGRHHR GRGGEPRAYF MSDTREEKRF LGEGHHRVQE NQMDKARRHP QGAWKELDRN YLNYGEEGAP GKWQQQGDLQ DTKENREEAR FQDKQYSSHH TAEKRKRLGE LFNPYYDPLQ WKSSHFERRD NMNDNFLEGE EENELTLNEK NFFPEYNYDW WEKKPFSEDV NWGYEKRNLA RVPKLDLKRQ YDRVAQLDQL LHYRKKSAEF PDFYDSEEPV STHQEAENEK DRADQTVLTE DEKKELENLA AMDLELQKIA EKFSQRG|
|Background||CHGB, also known as secretogranin-1 or chromogranin-B, is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides. This protein Belongs to the chromogranin/secretogranin protein family and is expressed in the adrenal medulla, and in pheochromocytoma. Recombinant CHGB protein was expressed in E.coli and purified by using conventional chromatography techniques.|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, and 100 mM NaCl.|
|Intended Use||For Research Use Only|
|Molecular Weight||28.1 kDa (271aa), confirmed by MALDI-TOF.|
|NCBI Accession #||AAH00375|
|Purity||> 80% by SDS-PAGE|
|References||Benjannet S., et al. (1987) FEBS Lett. 224(1):142-8.
Gill BM., et al. (1991) Regul Pept. 33(2):223-35.
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||SCG1, Chromogranin-B, Secretogranin-1 Secretogranin I, Cg B, CHGB, ChromograninB, Secretogranin 1, Secretogranin B, SgI.|
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