| Product Name | Chicken High mobility group protein B2 (HMGB2) ELISA Kit |
|---|---|
| Description | Chicken High mobility group protein B2 (HMGB2) ELISA Kit has high sensitivity and excellent specificity for detection of Chicken HMGB2. No significant cross-reactivity or interference between Chicken HMGB2 and analogues was observed. High mobility group protein B2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. This Chicken High mobility group protein B2 (HMGB2) ELISA Kit employs a two-site sandwich ELISA to quantitate HMGB2 in samples. An antibody specific for HMGB2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyHMGB2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for HMGB2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of HMGB2 bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | HMGB2, HMG2, high-mobility group (nonhistone chromosomal) protein 2 |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Chicken |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Gene Id | 396482 |
| Storage | 2-8°C |
| Supplier | Abbkine |
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