CHP, 1-195aa, Human

Proteins, Recombinant
More Information
Product Name CHP, 1-195aa, Human
Background CHP (Calcium-binding protein P22) is a phosphoprotein that binds to the sodium-hydrogen exchangers (NHEs). This protein serves as an essential cofactor which supports the physiological activity of NHE family members. It has protein sequence similarity to calcineurin B and it is also known to be an endogenous inhibitor of calcineurin activity. Recombinant human CHP, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Species Human
Synonyms SLC9A1BP, Calcineurin B homolog, Calcineurin homologous protein, Calcium-binding protein p22, Calcium binding protein CHP, Sid 470, Sid470, SLC9A1 binding protein, Wrch2
Host E.coli
Tag His-tag
Molecular Weight 23.5 kDa(210aa), confirmed by MALDI-TOF
Form Liquid, in 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol
Concentration 1 mg/ml (determined by Bradford assay)
Purity > 95% by SDS-PAGE
Applications SDS-PAGE
NCBI NP_009167
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Shigekawa M., et al. (2001) J Biol Chem. 276(20):17367-72.
Kojima C., et al (2007) J Biol Chem. 282(4):2741-51.

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