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|Product Name||CIAPIN1, 1-312aa Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSMADFGIS AGQFVAVVWD KSSPVEALKG LVDKLQALTG NEGRVSVENI KQLLQSAHKE SSFDIILSGL VPGSTTLHSA EILAEIARIL RPGGCLFLKE PVETAVDNNS KVKTASKLCS ALTLSGLVEV KELQREPLTP EEVQSVREHL GHESDNLLFV QITGKKPNFE VGSSRQLKLS ITKKSSPSVK PAVDPAAAKL WTLSANDMED DSMDLIDSDE LLDPEDLKKP DPASLRAASC GEGKKRKACK NCTCGLAEEL EKEKSREQMS SQPKSACGNC YLGDAFRCAS CPYLGMPAFK PGEKVLLSDS NLHDA|
|Background||Anamorsin, also known as CIAPIN1, is primarily expressed in the cytoplasm of liver, pancreas and heart tissue cells and does not show any homology to known apoptosis regulatory molecules of the Bcl-2 or CASP families, or to signal transduction molecules. Expression of CIAPIN1 is dependent on growth factor stimulation. It is a ubiquitously expressed protein, and when it is overexpressed, it confers apoptotic resistance. Recombinant human CIAPIN1protein, fused to His-tag at N-terminus, was expressed in E.coli.|
|Concentration||0.25 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol.|
|Intended Use||For Research Use Only|
|Molecular Weight||16 kDa (148aa) confirmed by MALDI-TOF|
|NCBI Accession #||NP_064709|
|Purity||> 90% by SDS-PAGE|
|References||Shibayama H., et al. (2011) Am J Hum Genet. 88(5):608-15.
Hao Z., et al. (2005) Hybridoma. 24:141-145.
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||Anamorsin, DRE2, PRO0915|
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