CRABP1, 1-137aa, Human, Recombinant

Category: Proteins
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01-2018-1
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Product Name CRABP1, 1-137aa, Human, Recombinant
Description CRABP1, also known as cellular retinoic acid-binding protein 1, is a member of specific carrier proteins for members of the vitamin A family. This protein is assumed to play an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid. It is constitutively expressed and is believed to have different functions in the cell than the related CRABP2. Recombinant CRABP1 protein was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms CRABP, CRABP-I, CRABPI, RBP5, Cellular retinoic acid binding protein 1 CRABP 1, CRABP I, RBP 5, Retinoic acid binding protein I cellular.
Host E.coli
Molecular Weight 31.5 kDa (277aa), confirmed by MALDI-TOF.
Amino Acid Sequence MPNFAGTWKM RSSENFDELL KALGVNAMLR KVAVAAASKP HVEIRQDGDQ FYIKTSTTVR TTEINFKVGE GFEEETVDGR KCRSLATWEN ENKIHCTQTL LEGDGPKTYW TRELANDELI LTFGADDVVC TRIYVRE
Reactivity Human
Applications SDS-PAGE
Form Liquid, in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.
Concentration 1 mg/ml (determined by Bradford assay)
Purity > 95% by SDS-PAGE
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
References Wang L, et al. (1997) J Biol Chem, 272(3):1541-7.
Astrom A, et al. (1991) J Biol Chem, 266(26):17662-6.
Supplier ARP

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