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|Product Name||CRYZL1, 1-349aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MKGLYFQQSS TDEEITFVFQ EKEDLPVTED NFVKLQVKAC ALSQINTKLL AEMKMKKDLF PVGREIAGIV LDVGSKVSFF QPDDEVVGIL PLDSEDPGLC EVVRVHEHYL VHKPEKVTWT EAAGSIRDGV RAYTALHYLS HLSPGKSVLI MDGASAFGTI AIQLAHHRGA KVISTACSLE DKQCLERFRP PIARVIDVSN GKVHVAESCL EETGGLGVDI VLDAGVRLYS KDDEPAVKLQ LLPHKHDIIT LLGVGGHWVT TEENLQLDPP DSHCLFLKGA TLAFLNDEVW NLSNVQQGKY LCILKDVMEK LSTGVFRPQL DEPIPLYEAK VSMEAVQKNQ GRKKQVVQF|
|Background||CRYZL1, also known as quinone oxidoreductase, is a protein that has sequence similarity to zeta crystalline. This Protein is present at low levels in human lens tissue. It has NADPH-dependent quinone reductase activity distinct from other known quinone reductases, and may play a role as a pH response element-binding protein. CRYZL1 is expressed at various levels in heart, brain, skeletal muscle, kidney, pancreas, liver and lung. Recombinant human CRYZL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl|
|Intended Use||For Research Use Only|
|Molecular Weight||21.5 kDa (188aa), confirmed by MALDI-TOF|
|NCBI Accession #||NP_665857|
|Purity||> 95% by SDS-PAGE|
|References||Cai SF., et al. (2009) Molecules. 14(8):2935-46.
Tauraite D., et al. (2009) Chem Phys Lipids. 159(1):45-50.
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||4P11, QOH-1, Quinone oxidoreductase-like protein 1 QOH 1, QOH1, Quinone oxidoreductase like 1, Quinone reductase like 1, Zeta crystallin homolog,|
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