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|Product Name||CST6, 29-149aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MRPQERMVGE LRDLSPDDPQ VQKAAQAAVA SYNMGSNSIY YFRDTHIIKA QSQLVAGIKY FLTMEMGSTD CRKTRVTGDH VDLTTCPLAA GAQQEKLRCD FEVLVVPWQN SSQLLKHNCV QM|
|Background||CST6 is a member of the type 2 cystatin family. Some of the members are active cysteine protease inhibitors, while cystatin E/M moderate the inhibition of cathepsin B but is not active against cathepsin C. CST6 is secretable proteins that influence osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and the response to systemic inflammation. Recombinant human CST6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Concentration||0.5 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl|
|Intended Use||For Research Use Only|
|Molecular Weight||26.4 kDa (232aa)|
|NCBI Accession #||NP_001314|
|Purity||> 95 % by SDS-PAGE|
|References||Ni J., et al. (1997) J Biol Chem. 272(16):10853-8.
Saitoh E., et al. (1988) Biol Chem Hoppe Seyler. 369:191-7.
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||Cystatin-M, Cystatin E/M, Cystatin M, Cystatin-E, Cystatin-6|
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