CTNNBIP1, 1-81aa, Human

Catalog
01-1861-1
$0.00
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Proteins, Recombinant
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Product Name CTNNBIP1, 1-81aa, Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MNREGAPGKS PEEMYIQQKV RVLLMLRKMG SNLTASEEEF LRTYAGVVNS QLSQLPPHSI DQGAEDVVMA FSRSETEDRR Q
Applications SDS-PAGE
Background CTNNBIP1 binds CTNNB1 and prevents interaction between CTNNB1 and TCF (T-cell transcription factor) family members. This protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. Recombinant human CTNNBIP1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography
Concentration 0.5 mg/ml (determined by Bradford assay)
Form Liquid, in 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol
Species Human
Host E.coli
Intended Use For Research Use Only
Molecular Weight 18.9 kDa(173aa), confirmed by MALDI-TOF
NCBI Accession # NP_064633
Purity > 90% by SDS-PAGE
References Tago K., et al. (2000) Genes Dev. 14 (14): 1741-9.
Daniels D.L., et al. (2002) Mol Cell 10:573-584
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms ICAT, Beta-catenin-interacting protein 1, Beta catenin interacting protein1, Beta catenin interacting protein ICAT, Catenin beta interacting protein 1, CTNNBIP 1, ICAT, Inhibitor of beta catenin and Tcf 4, MGC15093

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