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|Product Name||CUTA, 33-179aa, Human|
|Amino Acid Sequence||MRLLLLPRVL LTMASGSPPT QPSPASDSGS GYVPGSVSAA FVTCPNEKVA KEIARAVVEK RLAACVNLIP QITSIYEWKG KIEEDSEVLM MIKTQSSLVP ALTDFVRSVH PYEVAEVIAL PVEQGNFPYL QWVRQVTESV SDSITVLPLE HHHHHH|
|Background||CUTA, also known as ACHAP (acetylcholinesterase-associated protein), is the 179 amino acid mammalian homolog of the cutA E. coli protein and is ubiquitously expressed, particularly in brain tissue. CUTA is thought to be involved in cellular tolerance to a wide variety of divalent cations other than copper. The CUTA protein is a cytoplasmic protein, encoded by the single-gene operon and has been linked to divalent cation tolerance. Recombinant human CUTA protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Concentration||0.5 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20 mM Tris-HCl buffer (pH8.0) containing 5mM DTT, 0.2 M NaCl, and 20% glycerol|
|Intended Use||For Research Use Only|
|Molecular Weight||87.3 kDa (800aa), confirmed by MALDI-TOF|
|NCBI Accession #||NP_001014840|
|Purity||> 95% by SDS-PAGE|
|References||Liang D., et al. (2009) FEBS J. 276(16):4473-82.
Takubo K., et al. (2009) Anticancer Drugs. 20(8):668-75.
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||ACHAP, C6orf82, MGC111154, Acetylcholinesterase Associated Protein, Brain Acetylcholinesterase Putative Membrane Anchor, C6ORF82, CutA Divalent Cation Tolerance Homolog, CutA1, OTTHUMP00000039621, RP4570F34.|
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