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|Product Name||Cyclophilin G, 1-175aa, Humanged,|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGIKVQRPRC FFDIAINNQP AGRVVFELFS DVCPKTCENF RCLCTGEKGT GKSTQKPLHY KSCLFHRVVK DFMVQGGDFS EGNGRGGESI YGGFFEDESF AVKHNKEFLL SMANRGKDTN GSQFFITTKP TPHLDGHHVV FGQVISGQEV VREIENQKTD AASKPFAEVR ILSCG|
|Background||: Peptidyl-prolyl cis-trans isomerase G (PPIG), also known as Cyclophilin G, is a member of peptidyl-prolyl cis-trans isomerase family (PPIases). This protein catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and is implicated in the folding, transport, and assembly of proteins. It is localized to the nuclear speckles, a nuclear compartment rich in splicing factors, and interacts with the splicing factors SC35 and pinin. Cyclophilin G also may play an important role in the regulation of pre-mRNA splicing. Recombinant human Cyclophilin G, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol|
|Intended Use||For Research Use Only|
|Molecular Weight||64.8 kDa (563aa)|
|NCBI Accession #||AAH01555|
|Purity||> 95% by SDS-PAGE|
|References||Modjtahedi N., et al. (2004). J Biol Chem. 279(21):22322-30
Ouyang P., et al. (2004). Biochem Biophys Re Commun. 321 (3): 638-47
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||PPIase G, Rotamase G, Cyclophilin G, CASP10, PPIG, Peptidyl-prolyl cis-trans isomerase G,peptidylprolyl isomerase G (cyclophilin G), CARS-Cyp, SRCyp, SCAF10, SR-related CTD-associated factor 10,|
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