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|Product Name||CYGB, 1-190aa, Human|
|Background||CYGB is a globin molecule located in the brain and most notably utilized in marine mammals. It is thought to be a method of protection under conditions of hypoxia. The predicted function of cytoglobin is the modulation of oxygen and nitric oxide metabolism or scavenging free radicals within a cell. Recombinant human CYGB, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.|
|Synonyms||HGB, STAP, Cytoglobin, CYGB, Histoglobin, Stellate cell activation associated protein.|
|AA Sequence||MGSSHHHHHH SSGLVPRGSH MEKVPGEMEI ERRERSEELS EAERKAVQAM WARLYASCED VGVAILVRFF VNFPSAKQYF SQFKHMEDPL EMERSPQLRK HACRVMGALN TVVENLHDPD KVSSVLALVG KAHALKHKVE PVYFKILSGV ILEVVAEEFA SDFPPETQRA WAKLRGLIYS HVTAAYKEVG WVQQVPNATT PPATLPSSGP|
|Molecular Weight||45 kDa (397aa), confirmed by MALDI-TOF|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 1mM EDTA, 50mM NaCl|
|Concentration||1mg/ml (determined by Bradford assay)|
|Purity||> 90% by SDS-PAGE|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Hankeln T., et al. (2002) Mol Biol Evol. 19(4):416-21
Gazdar AF., et al. (2008) Cancer Res. 68(18):7448-56
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