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|Product Name||DECR2, 1-292aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSMAQPPPD VEGDDCLPAY RHLFCPDLLR DKVAFITGGG SGIGFRIAEI FMRHGCHTVI ASRSLPRVLT AARKLAGATG RRCLPLSMDV RAPPAVMAAV DQALKEFGRI DILINCAAGN FLCPAGALSF NAFKTVMDID TSGTFNVSRV LYEKFFRDHG GVIVNITATL GNRGQALQVH AGSAKAAVDA MTRHLAVEWG PQNIRVNSLA PGPISGTEGL RRLGGPQASL STKVTASPLQ RLGNKTEIAH SVLYLASPLA SYVTGAVLVA DGGAWLTFPN GVKGLPDFAS FSAKL|
|Background||DECR2, also known as peroxisomal 2,4-dienoyl-CoA reductase, is an auxiliary enzyme of beta-oxidation. DECR2 participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. This protein catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Recombinant human DECR2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.|
|Concentration||0.25 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH7.5) containing 40% glycerol, 0.15M NaCl, 1mM DTT|
|Intended Use||For Research Use Only|
|Molecular Weight||24.1 kDa (210aa), confirmed by MALDI-TOF|
|NCBI Accession #||NP_065715|
|Purity||> 95% by SDS-PAGE|
|References||De Nys K., et al. (2001) Biochim. Biophys. Acta. 1533:66-72
Daniels R.J., et al. (2001) Hum. Mol. Genet. 10:339-352
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||Peroxisomal 2,4-dienoyl-CoA reductase, PDCR, SDR17C1|
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