| Product Name | Dicer Antibody: APC |
|---|---|
| Description | Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs) (1). After long primary transcript pri-miRNAs are processed to stem-looped pre-miRNAs by Drosha (2), pre-miRNAs are transported to the cytoplasm and further processed by Dicer to produce 22-nucleotide mature miRNAs (3). The mature miRNA then becomes a part of the RNA-Induced Silencing Complex (RISC) and can bind to the 3' UTR of the target mRNA (3). Mouse Anti-Mouse Dicer Monoclonal IgG1 |
| Synonyms | Dicer1 Antibody, DCR Antibody, DCR1 Antibody, DCR-1 Antibody, Double-strand-specific ribonuclease Antibody, Helicase with RNase motif Antibody, HERNA Antibody, Helicase MOI Antibody, KIAA0928 Antibody, Endoribonuclease Dicer Antibody |
| Host | Mouse |
| Clone | S167-7 |
| Immunogen | Fusion protein amino acids 1638-1899 of mouse Endoribonuclease Dicer |
| Isotype | IgG1 |
| Specificity | Detects ~215kDa. |
| Reactivity | Human, Mouse, Rat |
| Applications | ICC, IF, WB |
| Form | Purified, in PBS pH7.4, 50% glycerol, 0.09% sodium azide |
| Gene Id | NP_683750.2. 192119 |
| Uniprot | Q8R418 |
| Supplier | Stressmarq Biosciences |
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