EIF5A2, 1-153aa, Human

Proteins, Recombinant
More Information
Product Name EIF5A2, 1-153aa, Human
Background EIF5A2, a member of eukaryotic initiation factor 5A subfamily, is an essential protein tightly linked to cellular polyamine homeostasis. The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond during the initial stage of protein synthesis. It seems to be the only eukaryotic protein to have a hypusine residue, which is a post-translational modification of a lysine by the addition of a butylamino group. Recombinant human EIF5A2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Species Human
Synonyms Eukaryotic translation initiation factor 5A2, Eukaryotic translation initiation factor 5A2, eIF 5A 2, eIF 5A2, eIF5AII, Eukaryotic initiation factor 5A isoform 2, eIF-4D, EIF5A 2, EIF5A2, Eukaryotic translation initiation factor 5A2, MGC124092, MGC124093
Host E.coli
Molecular Weight 38.3kDa(353aa), confirmed by MALDI-TOF
Form Liquid, in 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol
Concentration 0.5 mg/ml (determined by Bradford assay)
Purity > 85% by SDS-PAGE
Applications SDS-PAGE
NCBI NP_065123
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Guan XY., et al. (2010) Hepatology. 51(4):1255-63.
Luk JM., et al. (2009) Int J Cancer. 127(4):968-76.

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