| Product Name | FIH Antibody: ATTO 565 |
|---|---|
| Description | FIH, Factor inhibiting HIF1 (hypoxia-inducible factor), is an asparaginyl hydroxylase. FIH in conjunction with VHL represses HIF-1 transcriptional activity by disrupting the interaction of HIF-1 with the transcriptional co-activators CBP/p300, and by recruiting histone deacetylases. FIH activity is inhibited during hypoxia (1-3). Recent studies show that low nuclear expression of FIH is a strong independent prognostic factor for a poor overall survival in clear cell renal cell carcinoma (4). Mouse Anti-Human FIH Monoclonal IgG1 |
| Synonyms | Factor inhibiting HIF1 (hypoxia-inducible factor) Antibody, DKFZp762F1811 Antibody, Factor inhibiting HIF-1 Antibody, Factor inhibiting HIF1 Antibody, FIH 1 Antibody, FIH-1 Antibody, FIH1 Antibody, FLJ20615 Antibody, FLJ22027 Antibody, HIF1AN Antibody, HI |
| Host | Mouse |
| Clone | FIH 162c |
| Immunogen | Full length human FIH expressed in E.coli BL21 (DE3) cells |
| Isotype | IgG1 |
| Specificity | Detects ~45kDa. |
| Reactivity | Human, Mouse |
| Applications | ICC, IF, IHC, WB |
| Form | Purified, in PBS pH7.4, 50% glycerol, 0.09% sodium azide |
| Gene Id | NP_060372.2. 55662 |
| Uniprot | Q9NWT6 |
| Supplier | Stressmarq Biosciences |
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