GAL, 20-123aa, Human

Proteins, Recombinant
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Product Name GAL, 20-123aa, Human
Applications SDS-PAGE
Background Galanin peptides preproprotein, also known as GAL, is localized in brain pathways involved in both cognition and affect, and may inhibit learning and memory by inhibiting neurotransmitter release and neuronal firing rate. It modulates a variety of physiological processed including cognition/memory, sensory/pain processing, neurotransmitter/hormone secretion, and feeding behavior. GAL is upregulated in primary afferent and sympathetic neurones and may be involved in the development of sympathetic perineuronal baskets (“rings”) following nerve injury. Recombinant human GAL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Species Human
Host E.coli
Intended Use For Research Use Only
Molecular Weight 19 kDa (170aa)
NCBI Accession # NP_057057
Purity > 90% by SDS-PAGE
References Steiner R A., et al. (2001) Proc Natl Acad Sci USA. 4184-4189
Kleine B., et al. (2001) Mol Hum Reprod. 7:379-385.
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms Galanin peptides preproprotein, GALN, GLNN, GMAP
Tag His-tag

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