| Product Name | Histone H3 Antibody (tri Methyl Lys79): FITC |
|---|---|
| Description | Histone H3 is a 17 kD nuclear protein that is a component of an octamer containing pairs of each of four core histones (H2A, H2B, H3, H4). The core histones create nucleosome structure of chromosomal fiber in eukaryotes and are dynamic in gene regulation. The histones exhibit cell cycle-dependent transcriptional regulation except for the variant H3.3 which is cell cycle-independent. Histone H3 can be modified by phosphorylation, acetylation, ubiquitination, ribosylation, and methylation. Histone H3 has been shown to interact with Rsk-2, MSK1, GCN5 family of HATs, HDACs, PARP, SET7/9, and CARM1. Histones play a cental role in transcription regulation, DNA repair, DNA replication and chromosomal stability. . Mouse Anti-Human Histone H3 (tri Methyl Lys79) Monoclonal IgG1 |
| Synonyms | H3 histone family, member A Antibody, H3/A Antibody, H31_HUMAN Antibody, H3FA Antibody, Hist1h3a Antibody, histone 1 H3a Antibody, Histone cluster 1 H3a Antibody, Histone H3.1 Antibody |
| Host | Mouse |
| Clone | 5D8 |
| Immunogen | Prepared by immunizing synthetic peptide coupled to KLH. |
| Isotype | IgG1 |
| Specificity | Detects endogenous Histone H3 (tri methyl K79) protein. |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Form | Purified, in PBS (without Mg2+ and Ca2+), 50% glycerol, pH 7.4, 150mM NaCl, 0.02% sodium azide |
| Uniprot | P68431/Q71DI3/P84243 |
| Supplier | Stressmarq Biosciences |
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