| Product Name | HSP47 Antibody: ATTO 565 |
|---|---|
| Description | HSP47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of HSP47 around fibrotic lesions (1). The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since HSP47 binds a single substrate (2). Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils (3). . Mouse Anti-Human HSP47 Monoclonal IgG1 Kappa |
| Synonyms | SerpinH1 Antibody, Colligin Antibody, Gp46 Antibody, serine proteinase inhibitor Antibody, cysteine proteinase inhibitor Antibody, collagen binding protein Antibody |
| Host | Mouse |
| Clone | 1C4-1A6 |
| Immunogen | Human HSP47, full length |
| Isotype | IgG1 kappa |
| Specificity | Detects 47kDa. |
| Reactivity | Human |
| Applications | ICC, IF, WB |
| Form | Purified, in PBS pH7.4, 50% glycerol, 0.09% sodium azide |
| Gene Id | NP_001193943. 871 |
| Uniprot | P50454.2 |
| Supplier | Stressmarq Biosciences |
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