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|Product Name||HSPB3, 1-150aa, Human|
|Background||HSPB3, also known as HSPL27, is a muscle-specific small heat shock protein. It is expressed preferentially in heart and skeletal muscle. Mammalian small heat shock proteins (sHSP) is a abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. HSPB3 functions as an ATP-dependent chaperone protein that plays a role in the refolding of denatured proteins and may also Inhibitor of actin polymerization.|
|Synonyms||Heat shock protein beta-3, DHMN2C, HMN2C, HSPL27|
|AA Sequence||MGSSHHHHHH SSGLVPRGSH MAKIILRHLI EIPVRYQEEF EARGLEDCRL DHALYALPGP TIVDLRKTRA AQSPPVDSAA ETPPREGKSH FQILLDVVQF LPEDIIIQTF EGWLLIKAQH GTRMDEHGFI SRSFTRQYKL PDGVEIKDLS AVLCHDGILV VEVKDPVGTK|
|Molecular Weight||31.0 kDa (276aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol|
|Concentration||1.0 mg/ml (determined by Bradford assay)|
|Purity||> 85 % by SDS-PAGE|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Fontaine JM., et al. (2005) Biochem Biophys Res Commun. 337(3):1006-11.
Suqiyama Y., et al. (2000) J Biol Chem. 275(2):1095-104.
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