HSPB3, 1-150aa, Human

Proteins, Recombinant
More Information
Product Name HSPB3, 1-150aa, Human
Background HSPB3, also known as HSPL27, is a muscle-specific small heat shock protein. It is expressed preferentially in heart and skeletal muscle. Mammalian small heat shock proteins (sHSP) is a abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. HSPB3 functions as an ATP-dependent chaperone protein that plays a role in the refolding of denatured proteins and may also Inhibitor of actin polymerization.
Species Human
Synonyms Heat shock protein beta-3, DHMN2C, HMN2C, HSPL27
Host E.coli
Tag His-tag
Molecular Weight 31.0 kDa (276aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol
Concentration 1.0 mg/ml (determined by Bradford assay)
Purity > 85 % by SDS-PAGE
Applications SDS-PAGE
NCBI NP_006299
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Fontaine JM., et al. (2005) Biochem Biophys Res Commun. 337(3):1006-11.
Suqiyama Y., et al. (2000) J Biol Chem. 275(2):1095-104.

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