| Product Name | Human Serine/threonine-protein kinase PLK3 (PLK3) ELISA Kit |
|---|---|
| Description | CNK is a member of the 'polo' family of serine/threonine kinases. Members of this family have been implicated in cell division and are important in regulating the onset of mitosis and M-phase progression.The predicted 607-amino acid protein has an N-terminal catalytic domain, including an ATP-binding site, a central putative nuclear targeting signal, and a presumed C-terminal regulatory domain. The CNK protein shows homology with several other members of the 'polo' family; it is 91% identical to mouse Fnk, 50% identical to human PLK, 48% identical to Drosophila polo, and 38% identical to S. cerevisiae Cdc5. Northern blot analysis detected expression of a 2.5-kb CNK transcript in a limited number of human tissues, with placenta containing a moderate level and ovary, lung, and peripheral blood leukocytes containing low levels. This assay has high sensitivity and excellent specificity for detection of Human PLK3. No significant cross-reactivity or interference between Human PLK3 and analogues was observed. |
| Synonyms | RP11-269F19.6, CNK, FNK, PRK, FGF-inducible kinase|cytokine-inducible kinase|polo-like kinase 3|proliferation-related kinase |
| Method | Sandwich ELISA |
| Detection Range | 23.44-1500 pg/mL |
| Sensitivity | 5.8 pg/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Supplier | Abebio |
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