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|Product Name||ING2, 1-280aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSMLGQQQQ QLYSSAALLT GERSRLLTCY VQDYLECVES LPHDMQRNVS VLRELDNKYQ ETLKEIDDVY
EKYKKEDDLN QKKRLQQLLQ RALINSQELG DEKIQIVTQM LELVENRARQ MELHSQCFQD PAESERASDK AKMDSSQPER SSRRPRRQRT
SESRDLCHMA NGIEDCDDQP PKEKKSKSAK KKKRSKAKQE REASPVEFAI DPNEPTYCLC NQVSYGEMIG CDNEQCPIEW FHFSCVSLTY
KPKGKWYCPK CRGDNEKTMD KSTEKTKKDR RSR
|Background||The ING2 is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. Recombinant human ING2 protein, fused to His-tag at N-terminus, was expressed in E.coli.|
|Concentration||0.5 mg/ml (determined by BCA assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT|
|Intended Use||For Research Use Only|
|Molecular Weight||13.9 kDa (125aa) confirmed by MALDI-TOF|
|NCBI Accession #||NP_001555|
|Purity||> 85% by SDS-PAGE|
|References||Ythier,D., et al. (2010) Oncogene 29 (44), 5946-5956
Larrieu,D., et al. (2010) Cell Cycle 9 (19), 3984-3990
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
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