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|Product Name||ITGB1BP3, 1-230aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSMKLIVGI GGMTNGGKTT LTNSLLRALP NCCVIHQDDF FKPQDQIAVG EDGFKQWDVL ESLDMEAMLD TVQAWLSSPQ KFARAHGVSV QPEASDTHIL LLEGFLLYSY KPLVDLYSRR YFLTVPYEEC KWRRSTRNYT VPDPPGLFDG HVWPMYQKYR QEMEANGVEV VYLDGMKSRE ELFREVLEDI QNSLLNRSQE SAPSPARPAR TQGPGRGCGH RTARPAASQQ DSM|
|Background||Nicotinamide riboside kinase 2, also known as ITGB1BP3, belongs to the uridine kinase family and NRK subfamily. ITGB1BP3 is found at lower levels in heart and is downregulated during myoblast differentiation. ITGB1BP3 catalyzes the phosphorylation of nicotinic acid riboside and nicotinamide riboside to form nicotinic acid mononucleotide and nicotinamide mononucleotide. Recombinant human ITGB1BP3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Concentration||0.5 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 30% glycerol,1mM DTT|
|Intended Use||For Research Use Only|
|Molecular Weight||41.5 kDa (387aa), confirmed by MALDI-TOF|
|NCBI Accession #||NP_733778|
|Purity||> 90% by SDS-PAGE|
|References||Li J., et al. (1999) J Cell Biol. 147: 1391-1398
Li J., et al. (2003) Dev Biol. 261: 209-219.
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||Nicotinamide riboside kinase 2, MIBP, NRK2|
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