LRRK2/Dardarin Antibody: ATTO 655

Category: Antibodies
Catalog
SMC-445D-A655
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Product Name LRRK2/Dardarin Antibody: ATTO 655
Description LRRK2 is a large protein with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Ras-like small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. Several dominantly inherited missense mutations in the gene encoding LRRK2 have been identified in several families that exhibit a broad spectrum of neuropathological features. Mouse Anti-Human LRRK2/Dardarin Monoclonal IgG2a
Synonyms Leucine-rich repeat kinase 2 Antibody, RIP7 Antibody, PARK8 Antibody, Dardarin Antibody, ROCO 2 Antibody, RIPK7 Antibody, Leucine-rich repeat serine/threonine-protein kinase 2 Antibody, augmented in rheumatoid arthritis 17 Antibody
Host Mouse
Clone S231B-34
Immunogen Fusion protein amino acids 841-960 of human LRRK2. 81% identical in mouse, 80% identical in rat. <30% identity with LRRK1.
Isotype IgG2a
Specificity Detects >200kDa.
Reactivity Human, Rat
Applications ICC, IF, IHC, WB
Form Purified, in PBS pH 7.4, 50% glycerol, 0.1% sodium azide
Gene Id NP_940980. 120892
Uniprot Q5S007
Supplier Stressmarq Biosciences

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