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|Product Name||MMP23B, 79-254aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSYTLTPAR LRWDHFNLTY RILSFPRNLL SPRETRRALA AAFRMWSDVS PFSFREVAPE QPSDLRIGFY
PINHTDCLVS ALHHCFDGPT GELAHAFFPP HGGIHFDDSE YWVLGPTRYS WKKGVWLTDL VHVAAHEIGH ALGLMHSQHG RALMHLNATL
|Background||MMP23B is a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Recombinant human MMP23B protein, fused to His-tag at N-terminus, was expressed in E.coli.|
|Concentration||0.25 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 1mM DTT.|
|Intended Use||For Research Use Only|
|Molecular Weight||10.6 kDa (97aa) confirmed by MALDI-TOF|
|NCBI Accession #||NP_008914|
|Purity||> 85% by SDS-PAGE|
|References||Ohnishi J., et al. (2001) Mol. Endocrinol. 15:747-764
Velasco G., et al. (1999) J. Biol. Chem. 274:4570-4576
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||Matrix metallopeptidase 23B, MIFR, MIFR-1, MMP22, MMP23A|
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