| Product Name | Paraoxonase-1 (PON-1), human |
|---|---|
| Description | Recombinant human Paraoxonase-1 (rHuPON1). Paraoxonase 1 also called Esterase-A is involved in the detoxification of organophosphate insecticides such as parathion. Paraoxonase 1 may also confer protection against coronary artery disease by destroying proinflammatory oxidized lipids present in oxidized low-density lipoproteins (LDLs). Paraoxonase-1 Isoform Human Recombinant is expressed in E. coli having a molecular weight of 42.9 kDa and fused to a 4.5kDa amino terminal hexahistidine tag. |
| Synonyms | Mitogen-activated protein kinase 14, EC 2.7.11.24, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A, RK, p38, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, p38ALPHA |
| Molecular Weight | 42.9 kDa |
| Amino Acid Sequence | MAKLIALTLL GMGLALFRNH QSSYQTRLNA LREVQPVELP NCNLVKGIET GSEDLEILPN GLAFISSGLK YPGIKSFNPN SPGKILLMDL NEEDPTVLEL GITGSKFDVS SFNPHGISTF TDEDNAMYLL VVNHPDAKST VELFKFQEEE KSLLHLKTIR HKLLPNLNDI VAVGPEHFYG TNDHYFLDPY LRSWEMYLGL AWSYVVYYSP SEVRVVAEGF DFANGINISP DGKYVYIAEL LAHKIHVYEKHA NWTLTPLKSL DFNTLVDNIS VDPETGDLWV GCHPNGMKIF FYDSENPPAS EVLRIQNILT EEPKVTQVYA ENGTVLQGST VASVYKGKLL IGTVFHKALY CELZ |
| Applications | ELISA, IP, WB |
| Form | Purified, in 1X Laemli Buffer: 25mM Tris-HCl pH6.8, 50mM DTT, 1% SDS, 0.1% Bromophenol blue and 2.5% Glycerol |
| Purity | > 95% by SDS-PAGE |
| Storage | 2-8C for immediate use, or at -20C (aliquot) |
| Supplier | ARP |
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