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|Product Name||PDCD5, 1-125aa, Human, Recombinant|
|Amino Acid Sequence||MADEELEALR RQRLAELQAK HGDPGDAAQQ EAKHRGAEMR NSILAQVLDQ SARARLSNLA LVKPEKTKAV ENYLIQMARY GQLSEKVSEQ GLIEILKKVS QQTEKTTTVK LNRRKVMDSD EDDDY|
|Background||PDCD5 (Programmed cell death 5) encodes a protein expressed in tumor cells during apoptosis independent of the apoptosis-inducing stimuli. Prior to apoptosis induction, this gene product is distributed in both the nucleus and cytoplasm. The conformation of PDCD5 protein is a stable helical core consisting of a triple-helix bundle and two dissociated terminal regions. This is an important novel protein that regulates both apoptotic and non-apoptotic programmed cell death. Recombinant PDCD5 was expressed in E.coli and purified by using conventional chromatography techniques.|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20 mM Tris-HCl buffer (pH 8.0) containing 0.5mM DTT, 10% glycerol|
|Intended Use||For Research Use Only|
|Molecular Weight||25.1 kDa (225 aa), confirmed by MALDI-TOF.|
|NCBI Accession #||NP_004699|
|Purity||> 95% by SDS-PAGE|
|References||Chen Y., et al. (2001). FEBS Lett. 509(2):191-6.
Wang., et al. (2007). Apoptosis. 12(8):1433-41.
Liu D., et al. (2005). Biochem J. 392, 47-54.
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||TFAR19, Programmed cell death 5, PDCD5, Programmed cell death 5 Programmed cell death protein 5, TF-1 cell apoptosis-related protein 19, TFAR19 novel apoptosis-related.|
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