Anti-Grb2 Polyclonall Antibody

Category: Antibodies
Catalog
11-554-C100
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Product Name Anti-Grb2 Polyclonall Antibody
Description Grb2 (growth factor receptor-bound protein 2) is a highly conserved adaptor protein composed of central SH2 domain flanked by two terminal SH3 domains. Grb2 mediates coupling of receptor protein tyrosine kinases to a guanine nucleotide exchange factor Sos, thereby enabling the tyrosine kinases to stimulate activity of Ras and hence of MAP kinase pathway. Grb2 also can bind to receptor protein tyrosine phosphatases and affect their signaling.
Clone Polyclonal
Immunogen Synthetic peptide corresponding to C-terminus of human Grb2 (amino acids 198-217).
Specificity The polyclonal antibody recognizes Grb2, a highly conserved approximately 26 kDa adaptor protein. The immunogen has 100% identity between man, cow, rat and mouse.
Reactivity Human
Applications WB
Form The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
Storage Store at 2-8°C. Do not freeze.
Supplier Exbio

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