Anti-CD107a / LAMP-1 Monoclonal Antibody

Category: Antibodies
Catalog
A4-671-T100
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Product Name Anti-CD107a / LAMP-1 Monoclonal Antibody
Description CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation. The reagent is designed for Flow Cytometry analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension.The content of a vial (0.4 ml) is sufficient for 100 tests.
Clone H4A3
Immunogen Human PBMC
Isotype IgG1
Specificity The mouse monoclonal antibody H4A3 recognizes CD107a, an approximately 100-120 kDa glycoprotein expressed mainly on lysosomal, but also on the plasma membrane.
Reactivity Human, Mouse, Primate
Applications FC, ICC, IHC, WB
Form The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 0.02% sodium azide.
Storage Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Supplier Exbio

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