Anti-Adiponectin (clone 1G12)

Antibodies, Monoclonal Antibodies
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Product Name Anti-Adiponectin (clone 1G12)
Description Human Adiponectin, also referred to as AdipoQ, Acrp30, apm-1 or GBP28, is a secreted protein expressed exclusively in differentiated adipocyte(adipokine). Adiponectin contains a modular structure comprising an N-terminal collagenous domain followed by a C-terminal globular domain(gAcrp30). Adiponectin plays a role in various physiological processes such as energy homeostasis and obesity. Plasma levels of adiponectin are reduced in obese humans, and decreased levels are associated with insulin resistance and hyperinsulinemia.
Synonyms ADIPOQ, ACDC, ACRP30, APM1, GBP28, Adiponectin globular domain, Mouse, Adipocyte, C1q and collagen domain-containing protein, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, ACRP30, Adipose most abunda, Adiponectin, 30 kDa adipocyte complement related protein, ACRP 30, Adipocyte C1q and collagen domain containing protein, Adipocyte complement related 30 kDa protein, Adipocyte complement related protein of 30 kDa, Adipose most abundant gene transcript 1, APM 1, GBP 28, Gelatin binding protein,
Host Mouse
Clone 1G12. Anti-human adiponectin mAb, clone 1G12, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Acrp30 protein.
Immunogen Recombinant human adiponectin (15-244aa) purified from E. coli
Form Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
Reactivity Human, Mouse
Applications Cell lysate), Dot blot, ELISA, WB
Concentration 0.1 mg/ml
Working Dilutions Optimal dilution should be performed by user.
Species Mouse
Isotype IgG1, K
Interest Fields Hormones & Cytokines
NCBI Number NP_004788
Storage Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
References Maeda k. et al., (1996) Biochem Biophys Res Commun. 221:286-9. Berg AH. et al., (2001) Nat Med; 7:947-53 Berg AH. et al., (2002) Trends Endocrinol Metab. 13: 84-89. Yamauchi T. et al., (2002) Nat Med. 8:1288-95

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