Anti-KLK3 (AT1D10)

Catalog
01-A0228
$0.00
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Antibodies, Monoclonal Antibodies
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Product Name Anti-KLK3 (AT1D10)
Description Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. PSA is now used to indicate the presence of semen in forensic serology. The semen of adult males has PSA levels far in excess of those found in other tissues; therefore, a high level of PSA found in a sample is an indicator that semen may be present. Because PSA is a biomarker that is expressed independently of spermatozoa, it remains useful in identifying semen from vasectomized and azoospermic males.
Synonyms Prostate-specific antigen, APS, hK3, KLK2A1, PSA
Host Mouse
Clone AT1D10. Anti-human KLK3 mAb, clone AT1D10, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human KLK3 protein.
Immunogen Recombinant human KLK3(25-261aa) purified from E. coli
Form Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide
Reactivity Human
Applications Dot blot, ELISA, WB
Concentration 0.1 mg/ml
Working Dilutions Optimal dilution should be performed by user.
Species Mouse
Isotype IgG1, K
Interest Fields Cancer
NCBI Number NP_ 001648
Storage Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
References Balk SP, Ko YJ, Bubley GJ (January 2003). J. Clin. Oncol. 21 (2): 383€“91.Lilja H (November 2003). Urology 62 (5 Suppl 1): 27€“33.Rao AR, Motiwala HG, Karim OM (January 2008). BJU Int. 101 (1): 5€“10.

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