Anti-NSE (clone AT17D10)

Antibodies, Monoclonal Antibodies
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Product Name Anti-NSE (clone AT17D10)
Description Neuron-specific enolase (NSE) is a glycolytic isoenzyme which is located in central and peripheral neurons and neuroendocrine cells. This enzyme is released into the CSF when neural tissue is injured. Neoplasms derived from neural or neuroendocrine tissue may release NSE into the blood. NSE is a useful substance that has been detected in patients with certain tumors, namely: neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrine tumors, and melanoma.
Synonyms Enolase 2 (gamma, neuronal), ENO2, NSE, Neuron-Specific Enolase, 2 phospho D glycerate hydrolyase, Eno 2, ENOG, Enolase 2 gamma neuronal, Enolase2, Gamma enolase, Neural enolase, Neuron specific enolase, Neuron specific gamma enolase, Neurone specific enolase.
Host Mouse
Clone Anti-human NSE mAb, clone AT17D10, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NSE protein.
Immunogen Recombinant human NSE (1-434aa) purified from E. coli
Form Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide.
Reactivity Human
Applications Dot blot, ELISA, WB
Concentration 0.1mg/ml
Working Dilutions Optimal dilution should be performed by user.
Species Mouse
Isotype K, IgG2b
NCBI Number NP_001966
Storage Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
References Oliva D, Calì L, Feo S, Giallongo A (1991). Genomics 10 (1): 157€“65.Craig SP, Day IN, Thompson RJ, Craig IW (1991). Cytogenet. Cell Genet. 54 (1€“2): 71€“3.McAleese SM, Dunbar B, Fothergill JE, et al. (1989). Eur. J. Biochem. 178 (2): 413€“7.

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