Anti-OSTF1 (clone AT2F11)

Antibodies, Monoclonal Antibodies
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Product Name Anti-OSTF1 (clone AT2F11)
Description Osteoclast-stimulating factor (OSTF1) is an intracellular signaling protein, highly expressed by osteoclasts(OCL). Indirectly, it enhances osteoclast (OCL) formation and bone resorption through a cellular signal transduction cascade by possibly interacting with c-Src or other c-Src-related proteins. OSTF1 contains a short proline-rich N-terminal region, an SH3 domain, three ankyrin repeats and an aspartate-rich C-terminal region, suggesting that it is potentially involved in protein-protein interactions.
Synonyms SH3P2, OSF, Osteoclast stimulating factor 1
Host Mouse
Clone AT2F11. Anti-human OSTF1 mAb, clone AT2F11, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human OSTF1 protein.
Immunogen Recombinant human OSTF1 (1-217aa) purified from E. coli
Form Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide
Reactivity Human, Mouse
Applications Dot blot, ELISA, WB
Concentration 0.1 mg/ml
Working Dilutions Optimal dilution should be performed by user.
Species Mouse
Isotype IgG1, K
Interest Fields Signal Transduction
NCBI Number AAH07459
Storage Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
References Schaub R, et al. (2000). Cytogenet. Cell Genet. 88 (1-2): 87-8. Kurihara N, et al. (2001). J. Biol. Chem. 276 (44): 41035-9. Reddy S, et al. (Apr 1999). J Cell Physiol 177 (4): 636-45.

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