Antithrombin III

Catalog
12-7604
$0.00
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Proteins, Native Protein
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Product Name Antithrombin III
Description Antithrombin III is found in normal serum at 15mg per 100ml. Found at higher levels in plasma than in serum because of complexing with thrombin during coagulation. Functions in the inhibition of the proteolytic enzymes involved in blood coagulation and fibrinolysis, including factor Xa, plasmin, thrombin, and trypsin. Potency is strongly enhanced by heparin. Clinically, reduced levels are indicative of hypercoagulability.
Source Human plasma. Nonreactive and negative for HBsAg, anti-HCV, anti-HBc, and anti-HIV by FDA-required tests
Molecular Weight 65,000 Daltons
Concentration 1 mg/ml
Form Purified, in 50 mM Tris-HCl, pH 7.4, with 150 mM NaCl
Purity > 95% by SDS-PAGE
Storage 2-8C for immediate use, or at -20C (aliquot)

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