Prostagladin E synthase 3, 1-160aa, Human

Proteins, Recombinant
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Product Name Prostagladin E synthase 3, 1-160aa, Human
Applications SDS-PAGE
Background Prostaglandin E synthase 3 (PTGES3), also known as P23 or TEBP (Telomerase binding protein p23), is a ubiquitously expressed protein that functions as a cochaperone and plays an important role in signal transduction. This protein is a molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Recombinant PTGES3 protein was expressed in E.coli and purified by using conventional chromatography techniques.
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 20 mM Tris-HCl buffer ( pH8.0) containing 1mM DTT, 10% glycerol
Species Human
Host E.coli
Intended Use For Research Use Only
Molecular Weight 28.1 kDa (238aa), confirmed by MALDI-TOF.
NCBI Accession # NP_006592
Purity > 95% by SDS-PAGE
References Hawkins GA., et al. (2009) J Allergy Clin Immunol. 123(6):1376-83.e7
Nuttinck F., et al. (2008) Reproduction. 135(5):593-603.
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms PTGES3, cPGES, P23, TEBP, HSP90 co-chaperone, Sid 3177, Co chaperone p23, Hsp90 co chaperone, Cytosolic prostaglandin E2 synthase, Progesterone receptor complex, Progesterone receptor complex p23, Prostaglandin E synthase 3, PTGES 3, Telomerase binding protein p23, Unactive progesterone receptor 23 kD,
Tag His-tag

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