Protein kinase Casein Kinase 2 alpha (PKCK2, 1-391aa) Human, Recombinantged

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01-2267
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Proteins, Recombinant
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Product Name Protein kinase Casein Kinase 2 alpha (PKCK2, 1-391aa) Human, Recombinantged
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSGPVPSRAR VYTDVNTHRP REYWDYESHV VEWGNQDDYQ LVRKLGRGKY SEVFEAINIT NNEKVVVKIL KPVKKKKIKR EIKILENLRG GPNIITLADI VKDPVSRTPA LVFEHVNNTD FKQLYQTLTD YDIRFYMYEI LKALDYCHSM GIMHRDVKPH NVMIDHEHRK LRLIDWGLAE FYHPGQEYNV RVASRYFKGP ELLVDYQMYD YSLDMWSLGC MLASMIFRKE PFFHGHDNYD QLVRIAKVLG TEDLYDYIDK YNIELDPRFN DILGRHSRKR WERFVHSENQ HLVSPEALDF LDKLLRYDHQ SRLTAREAME HPYFYTVVKD QARMGSSSMP GGSTPVSSAN MMSGISSVPT PSPLGPLAGS PVIAAANPLG MPVPAAAGAQ Q
Applications SDS-PAGE
Background Protein Kinase Casein Kinase 2 (PKCK2, also called CK2) is a ubiquitous Ser/Thr kinase expressed in all eukaryotes. PKCK2 is a tetramer composed of two catalytic kinase domains, alpha subunits, and two identical regulatory beta subunits. It has been implicated in cell cycle control, DNA repair, regulation of the circadian rhythm, and other cellular processes. Recombinant human PKCK2, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in Phosphate Buffered Saline pH7.4
Species Human
Host E.coli
Intended Use For Research Use Only
Molecular Weight 54 kDa (495 aa), confirmed by MALDI-TOF.
NCBI Accession # NP_001886
Purity > 90% by SDS-PAGE
References Kim YK., et al. (2006) J Biol Chem. 281(48):36752-7.
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms CSNK2A1, CK2A1, Protein kinase Casein Kinase 2 alpha, PKCK2, CK II, EC 2.7.11.1, Casein kinase II subunit alpha, Casein kinase II alpha 1 subunit isoform a Casein kinase 2 alpha 1 polypeptide, Casein kinase II alpha 1 subunit, Casein kinase II alpha subunit, CK II, CK2 alpha, CK2 catalytic subunit alpha, CK2A1, CKII.
Tag His-tag

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