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|Product Name||RAB1B, 1-201aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MNPEYDYLFK LLLIGDSGVG KSCLLLRFAD DTYTESYIST IGVDFKIRTI ELDGKTIKLQ IWDTAGQERF RTITSSYYRG AHGIIVVYDV TDQESYANVK QWLQEIDRYA SENVNKLLVG NKSDLTTKKV VDNTTAKEFA DSLGIPFLET SAKNATNVEQ AFMTMAAEIK KRMGPGAASG GERPNLKIDS TPVKPAGGGC C|
|Background||RAB1B is a member of the RAB protein family, low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane bound organelles. This protein functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi. Recombinant human RAB1B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.|
|Concentration||0.5mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 100mM NaCl|
|Intended Use||For Research Use Only|
|Molecular Weight||22.7kDa (200aa), confirmed by MALDI-TOF|
|NCBI Accession #||NP_112243|
|Purity||> 90% by SDS-PAGE|
|References||Colombo MI., et al. (2010) Traffic. 11(9):1246-61.
Kawaoka Y., et al (2010) J Virol. 84(9):4816-20.
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||Ras-related protein Rab-1B,|
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