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|Product Name||RGS19, 1-217aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MPTPHEAEKQ ITGPEEADRP PSMSSHDTAS PAAPSRNPCC LCWCCCCSCS WNQERRRAWQ ASRESKLQPL PSCEVCATPS PEEVQSWAQS FDKLMHSPAG RSVFRAFLRT EYSEENMLFW LACEELKAEA NQHVVDEKAR LIYEDYVSIL SPKEVSLDSR VREGINKKMQ EPSAHTFDDA QLQIYTLMHR DSYPRFLSSP TYRALLLQGP SQSSSEA|
|Background||RGS19, also known as Regulator of G-protein signaling 19, belongs to RGS (regulator of G protein signaling) family and negatively regulates G protein coupled receptor signaling. This protein specifically interacts with heterotrimeric GTP-binding protein G alpha i3 (GAI3). Recombinant human RGS19 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.|
|Concentration||0.5mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 5mM DTT, 100mM NaCl|
|Intended Use||For Research Use Only|
|Molecular Weight||15.8kDa (144aa) confirmed by MALDI-TOF|
|NCBI Accession #||NP_001034556|
|Purity||> 90% by SDS-PAGE|
|References||Wong YH., et al. (2010) Cell Signal. 22(11):1700-7.
Farquhar MG., et al (1995) Proc Natl Acad Sci U S A. 92(25):11916-20.
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||Regulator of G-protein signaling 19, GAIP, GNAI3IP|
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