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|Product Name||RGS4, 1-205aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MCKGLAGLPA SCLRSAKDMK HRLGFLLQKS DSCEHNSSHN KKDKVVICQR VSQEEVKKWA ESLENLISHE CGLAAFKAFL KSEYSEENID FWISCEEYKK IKSPSKLSPK AKKIYNEFIS VQATKEVNLD SCTREETSRN MLEPTITCFD EAQKKIFNLM EKDSYRRFLK SRFYLDLVNP SSCGAEKQKG AKSSADCASL VPQCA|
|Background||RGS4(regulator of G protein signaling 4) is a protein which regulates G protein signaling. Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Recombinant human RGS4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Concentration||0.5 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 30% glycerol, 0.1M NaCl, 1mM EDTA|
|Intended Use||For Research Use Only|
|Molecular Weight||22.5 kDa (199aa), confirmed by MALDI-TOF|
|NCBI Accession #||NP_005604|
|Purity||> 90% by SDS-PAGE|
|References||Chowdari K.V., et al. (2002) Hum. Mol. Genet. 11:1373-1380
Tu Y., et al (1999) J. Biol. Chem. 274:38260-38267
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||Regulator of G-protein signaling 4, DKFZp761F1924, MGC2124, MGC60244, RGP4, SCZD9|
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