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|Product Name||S100A14, 1-104aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGQCRSANAE DAQEFSDVER AIETLIKNFH QYSVEGGKET LTPSELRDLV TQQLPHLMPS NCGLEEKIAN LGSCNDSKLE FRSFWELIGE AAKSVKLERP VRGH|
|Background||S100A14 is a member of a subfamily of proteins related by EF-hand Ca2+ binding protein superfamily. The extracellular functions of the S-100 family may include the ability to enhance neurite outgrowth, involvement in inflammation, and motility of tumor cells. S100A14 contains 2 EF-hand Ca2+-binding domains, a myristoylation motif, a glycosylation site, and several potential protein kinase phosphorylation sites. It is expressed at high level in the colon and at moderate level in the thymus, kidney, liver, small intestine, and lung. Recombinant human S100A14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Concentration||0.5 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.|
|Intended Use||For Research Use Only|
|Molecular Weight||15.1 kDa (140aa) confirmed by MALDI-TOF|
|NCBI Accession #||NP_065723|
|Purity||> 95% by SDS-PAGE|
|References||Wright NT., et al. (2005) J Mol Biol. 353(2):410-26.
Zimmer DB., et al. (2005) Cell Mol Biol. 51(2):201-14.
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||S100 calcium binding protein A14, BCMP84, S100A15|
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