| Product Name | Small Tailed Han Sheep Proopiomelanocortin (POMC) ELISA Kit |
|---|---|
| Description | Pro-opiomelanocortin (POMC) is a precursor polypeptide with 241 amino acid residues. This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. This assay has high sensitivity and excellent specificity for detection of Small Tailed Han Sheep POMC. No significant cross-reactivity or interference between Small Tailed Han Sheep POMC and analogues was observed. |
| Synonyms | ACTH, CLIP, LPH, MSH, NPP, POC, OTTHUMP00000119991|OTTHUMP00000200964|adrenocorticotropic hormone|adrenocorticotropin|alpha-MSH|alpha-melanocyte-stimulating hormone|beta-LPH|beta-MSH|beta-endorphin| |
| Method | Sandwich ELISA |
| Detection Range | 7.8-500 pg/mL |
| Sensitivity | 1.95 pg/mL |
| Reactivity | Sheep |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Supplier | Abebio |
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