STARD5, 1-213aa, Human

Category: Proteins
Catalog
01-P2435
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Product Name STARD5, 1-213aa, Human
Description StAR-related lipid transfer protein 5, also known as STARD5, belongs to the STARD family of proteins is comprised of fifteen different members. All members contain the characteristic START domain and are believed to play key roles in the metabolism and transport of lipids. The STARD proteins are grouped into six subfamilies based on their START domain sequences. STARD5 constitute one subfamily, sharing approximately 30% amino acid identity with each other. STARD5 is not sterol-regulated but can be induced by endomplasmic reticulum (ER) stress. Due to its exclusive tissue expression and its interaction with sterols, StARD6 may function in reproduction and germ cell maturation. Recombinant human STARD5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms 0
Host E.coli
Molecular Weight 44kDa (389aa), confirmed by MALDI-TOF
(Molecular size on SDS-PAGE will appear higher)
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMDPALAA QMSEAVAEKM LQYRRDTAGW KICREGNGVS VSWRPSVEFP GNLYRGEGIV YGTLEEVWDC
VKPAVGGLRV KWDENVTGFE IIQSITDTLC VSRTSTPSAA MKLISPRDFV DLVLVKRYED GTISSNATHV EHPLCPPKPG FVRGFNHPCG
CFCEPLPGEP TKTNLVTFFH TDLSGYLPQN VVDSFFPRSM TRFYANLQKA VKQFHE
Tag His-tag
Reactivity Human
Applications SDS-PAGE
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl,
20% glycerol, 1mM DTT
Concentration 0.5 mg/ml (determined by Bradford assay)
Purity > 95% by SDS-PAGE
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
References Soccio R E., et al. (2005) J Biol Chem. 280: 19410-19418.
Alpy F., et al. (2005) J Cell Sci. 118-2791-2801.
Supplier ARP

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