| Product Name | Anti-CD11b Monoclonal Antibody, FITC |
|---|---|
| Description | Mouse monoclonal Antibody to human CD11b FITC conjugate |
| Clone | AR44 |
| Immunogen | Antigen distribution: CD11b antigen is expressed on approximately 30% of human peripheral blood lymphocytes, most natural killer lymphocytes, circulating monocytes, granulocytes, a subset of T-cells and subsets of macrophages. |
| Isotype | Mouse IgG1 |
| Specificity | Recognizes the alpha subunit of the CD11b/CD18 complex, an alpha/beta heterodimeric surface glycoprotein on human leucocytes (MR 165-170 kDa). The CD11b/CD18 antigen belongs to the b2 intergrin family. Other names include Mac-1, Cr3, MO-1 and C3bi receptor. The CD11b molecule functions as a receptor for C3bi complement, clotting factor X, fibrinogen and ICAM-1. |
| Reactivity | Human |
| Form | Affinity purified, in 0.01M PBS, pH 7.2 containing 2mM EDTA, 1% BSA and 0.1% NaN3. F/P ratio is 5.03 |
| Storage | 2-8C for immediate use, or at -20C (aliquot) |
| Notes | This antibody may be used to study lymphocytes subsets in flow cytometry (recommended dilution: 1 ug to stain 1x106 cells) and in cell adhesion research (Mac-1). It may also be used to stain tissue sections which have been acetone fixed and frozen. |
| Supplier | ARP |
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