Anti-Human Apolipoprotein E (Apo E) Monoclonal Antibody

Category: Antibodies
Catalog
03-61085
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Product Name Anti-Human Apolipoprotein E (Apo E) Monoclonal Antibody
Description Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Mouse Monoclonal Antibody to Human Apolipoprotein E (Apo E). Human Apolipoprotein E (ApoE) exists in three common isoforms E2,E3, E4.
Synonyms AD2, LPG, LDLCQ5
Clone IB5-E1
Immunogen Human Apolipoprotein E
Isotype IgG1kappa
Specificity Mab 1B5-E1 reacts with all isoforms. The antibody detects a 38 kDa band in Western Blotting.
Reactivity Human
Applications ELISA, WB
Form Protein G Affinity purified
Storage 2-8C for immediate use, or at -20C (aliquot)
Supplier ARP

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