Aprataxin, 1-168aa, Human

Catalog
01-1782
$0.00
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Proteins, Recombinant
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Product Name Aprataxin, 1-168aa, Human
Background Aprataxin is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. Aprataxin may play a role in single-stranded DNA repair. Mutations in the gene have been associated with neurological disorder known as ataxia oculomotor apraxia-1. Recombinant Aprataxin protein was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms APTX, AXA1, AOA, AOA 1, AOA1, Aprataxin homolog, Ataxia 1 early onset with hypoalbuminemia, Ataxia1 early onset with hypoalbuminemia, AXA 1, EAOH, EOAHA, FHA HIT, FLJ20157, MGC1072, Forkhead associated domain histidine triad like, Forkhead associated domain histidine triad like protein.
Species Human
Amino Acid Sequence MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWAGSMQD PKMQVYKDEQ VVVIKDKYPK ARYHWLVLPW TSISSLKAVA REHLELLKHM HTVGEKVIVD FAGSSKLRFR LGYHAIPSMS HVHLHVISQD FDSPCLKNKK HWNSFNTEYF LESQAVIEMV QEAGRVTVRD GMPELLKLPL RCHECQQLLP SIPQLKEHLR KHWTQ
Molecular Weight 27.5 kDa (241aa), confirmed by MALDI-TOF.
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT 10% glycerol
Purity > 95% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_778241
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Kijas A.W., et al (2006) J. Biol. Chem. 281:13939-13948
Rass U., et al. (2007) J. Biol. Chem. 282:9469-9474
Host E.coli

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