ARPC2, 1-300aa, Human

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01-P2010
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Proteins, Recombinant
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Product Name ARPC2, 1-300aa, Human
Background Actin-related protein 2/3 complex subunit 2, also known as ARPC2, belongs to the Rho family of small GTPases. This protein is one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein, the p34 subunit, has yet to be determined. Recombinant human ARPC2L protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms Actin-related protein 2/3 complex subunit 2, ARC34, p34-Arc, PNAS-139, PRO2446
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMILLEVN NRIIEETLAL KFENAAAGNK PEAVEVTFAD FDGVLYHISN PNGDKTKVMV SISLKFYKEL QAHGADELLK RVYGSFLVNP ESGYNVSLLY DLENLPASKD SIVHQAGMLK RNCFASVFEK YFQFQEEGKE GENRAVIHYR DDETMYVESK KDRVTVVFST VFKDDDDVVI GKVFMQEFKE GRRASHTAPQ VLFSHREPPL ELKDTDAAVG DNIGYITFVL FPRHTNASAR DNTINLIHTF RDYLHYHIKC SKAYIHTRMR AKTSDFLKVL NRARPDAEKK EMKTITGKTF SSR
Molecular Weight 15.5 kDa (144aa) confirmed by MALDI-TOF
(Molecular size on SDS-PAGE will appear higher)
Concentration 0.25 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_005722
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Mullins R D., et al. (1998) Proc Natl Acad Sci USA. 95:6181-6186.
Syitkina T M., et al. (1999) J Cell Biol. 145:1009-1026.

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