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|Product Name||Biliverdin reductase B, 1-206aa, Human, Recombinant|
|Background||Biliverdin reductase B (BLVRB) is an enzyme (EC 220.127.116.11) that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. BLVRB is found that major erythrocytic heme catabolic pathway in humans and most mammalian species. Biliverdin reductase is abundantly expressed in kidney, spleen, liver and brain as well as at lower levels in the thymus and minimal levels being detected in testis. Recombinant BLVRB protein was expressed in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||BLVRB, FLR, BVRB, SDR43U1, MGC117413, Biliverdin reductase B, Biliverdin IX beta reductase, BVR B, Flavin reductase, Flavin reductase (NADPH), FR, GHBP, Green heme binding protein, MGC117413, NADPH dependent diaphorase, NADPH flavin reductase.|
|Amino Acid Sequence||MAVKKIAIFG ATGQTGLTTL AQAVQAGYEV TVLVRDSSRL PSEGPRPAHV VVGDVLQAAD VDKTVAGQDA VIVLLGTRND LSPTTVMSEG ARNIVAAMKA HGVDKVVACT SAFLLWDPTK VPPRLQAVTD DHIRMHKVLR ESGLKYVAVM PPHIGDQPLT GAYTVTLDGR GPSRVISKHD LGHFMLRCLT TDEYDGHSTY PSHQYQ|
|Molecular Weight||21 kDa (190 aa)|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris pH 8.0, 5mM DTT|
|Purity||> 95% by SDS-PAGE|
|NCBI Accession #||NP_000704.1|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||L. Lee Grismer., et al. (2007). Herpetologica. 63(3):392-400
Baranano DE., et al. (2002). Proc Natl Acad Sci USA. 99(25):16093-8
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