Biliverdin reductase B, 1-206aa, Human, Recombinant

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01-2021
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Proteins, Recombinant
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Product Name Biliverdin reductase B, 1-206aa, Human, Recombinant
Background Biliverdin reductase B (BLVRB) is an enzyme (EC 1.3.1.24) that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. BLVRB is found that major erythrocytic heme catabolic pathway in humans and most mammalian species. Biliverdin reductase is abundantly expressed in kidney, spleen, liver and brain as well as at lower levels in the thymus and minimal levels being detected in testis. Recombinant BLVRB protein was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms BLVRB, FLR, BVRB, SDR43U1, MGC117413, Biliverdin reductase B, Biliverdin IX beta reductase, BVR B, Flavin reductase, Flavin reductase (NADPH), FR, GHBP, Green heme binding protein, MGC117413, NADPH dependent diaphorase, NADPH flavin reductase.
Species Human
Amino Acid Sequence MAVKKIAIFG ATGQTGLTTL AQAVQAGYEV TVLVRDSSRL PSEGPRPAHV VVGDVLQAAD VDKTVAGQDA VIVLLGTRND LSPTTVMSEG ARNIVAAMKA HGVDKVVACT SAFLLWDPTK VPPRLQAVTD DHIRMHKVLR ESGLKYVAVM PPHIGDQPLT GAYTVTLDGR GPSRVISKHD LGHFMLRCLT TDEYDGHSTY PSHQYQ
Molecular Weight 21 kDa (190 aa)
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris pH 8.0, 5mM DTT
Purity > 95% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_000704.1
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References L. Lee Grismer., et al. (2007). Herpetologica. 63(3):392-400
Baranano DE., et al. (2002). Proc Natl Acad Sci USA. 99(25):16093-8

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