BRMS1, 1-246aa, Human, T7 tag

Catalog
01-P2502
$0.00
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Proteins, Recombinant
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Product Name BRMS1, 1-246aa, Human, T7 tag
Background BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. Recombinant human BRMS1 protein, fused to His-tag at N-terminus, was expressed in E.coli .
Synonyms Breast cancer metastasis suppressor 1, DKFZp564A063
Species Human
Amino Acid Sequence MASMTGGQQM GRGSHMPVQP PSKDTEEMEA EGDSAAEMNG EEEESEEERS GSQTESEEES SEMDDEDYER RRSECVSEML DLEKQFSELK EKLFRERLSQ LRLRLEEVGA ERAPEYTEPL GGLQRSLKIR IQVAGIYKGF CLDVIRNKYE CELQGAKQHL ESEKLLLYDT LQGELQERIQ RLEEDRQSLD LSSEWWDDKL HARGSSRSWD SLPPSKRKKA PLVSGPYIVY MLQEIDILED WTAIKKARAA VSPQKRKSDG P
Molecular Weight 14.4 kDa (128aa)
Concentration 0.25 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
Purity > 80% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_056214.1
Host E.coli
Tag T7 tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Meehan W.J., et al. (2004) J. Biol. Chem. 279:1562-1569.

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