CDK3, 1-305aa, Human

Catalog
01-P2169
$0.00
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Proteins, Recombinant
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Product Name CDK3, 1-305aa, Human
Background CDK3 is a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. Recombinant human CDK3 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Synonyms Cyclin-dependent kinase 3, CDKN3, Cell division protein kinase 3, Cyclin dependent kinase 3
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMDMFQKV EKIGEGTYGV VYKAKNRETG QLVALKKIRL DLEMEGVPST AIREISLLKE LKHPNIVRLL DVVHNERKLY LVFEFLSQDL KKYMDSTPGS ELPLHLIKSY LFQLLQGVSF CHSHRVIHRD LKPQNLLINE LGAIKLADFG LARAFGVPLR TYTHEVVTLW YRAPEILLGS KFYTTAVDIW SIGCIFAEMV TRKALFPGDS EIDQLFRIFR MLGTPSEDTW PGVTQLPDYK GSFPKWTRKG LEEIVPNLEP EGRDLLMQLL QYDPSQRITA KTALAHPYFS SPEPSPAARQ YVLQRFRH
Molecular Weight 14 kDa (126aa), confirmed by MALDI-TOF
Concentration 0.25 mg/ml (determined by BCA assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol.
Purity > 85% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_001249
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References MacLachlan T K., et al. (1995) Eukaryot Gene Expr. 5:127-156.
Braun K., et al. (1998) Oncogene. 17:2259-2269.

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